Trimi vs Willow

Both sell tirzepatide. Trimi costs $125 a month and Willow costs $399, a difference of $274 a month or about $3,288 a year. Here is what that difference actually buys.

Trimi is lowest flat price with named pharmacies. Willow is straightforward single-price plans. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though it usually is if you are paying cash and tolerate the medication well.

Put plainly. If you picked Trimi over Willow and everything else went the same way, you would be $3,288 better off after a year. Whether that is the right trade depends on the differences below, not on the number alone.

Side by side

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

What actually separates them

They differ on 3 of the 7 things we track. Those differences are what the price gap is buying.

What Trimi publishes

• Compounded tirzepatide advertised at $125/month on the annual plan.
• Compounded semaglutide advertised at $99/month on the annual plan.
• Medical oversight via Arora Health, a 50-state network led by Dr. Sean Arora, MD.
• Advertises a six-month money-back promise subject to terms.

Where it wins: The cheapest verified flat rate for compounded tirzepatide in this comparison. Watch for: Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months.

What Willow publishes

• Compounded tirzepatide listed at $399/month.

Where it wins: A single price with no membership arithmetic. Watch for: There is little published detail on how dose changes are handled. Ask before committing.

Where each is stronger

Trimi.

• The cheapest verified flat rate for compounded tirzepatide in this comparison.
• Names its pharmacies with a licence number and offers a certificate of analysis — almost nobody else in this market does.
• Price does not move as your dose is adjusted.
• No membership fee stacked on the medication price.

Willow.

• A single price with no membership arithmetic.

How they score

Trimi scores higher overall at 4.6 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which should you pick?

If you want the plain answer: Trimi, unless one of the differences above matters to you personally. Willow is not worse — it is aimed at somebody with a different problem, and paying $274 a month more for a problem you do not have is how people end up resenting a treatment that was working.

The verdict

We would tell a friend to start with Trimi and move if it disappointed them. That is not a strong claim about either company; it is what the arithmetic supports when nothing else is pulling you.

Full detail in the Trimi review and the Willow review.

How they sit against everyone else