Best of
The best tirzepatide providers in 2026
12 programmes compared on what you actually pay in month two — not the teaser rate. Coreage Rx comes first.
Updated 2026-09-18 · Prices verified independently
Why you can trust this: we take payment from one company on this page — Coreage Rx — when a reader signs up through our link. It does not change the prices we print or the rubric we score against, both of which are published in full on how we rate. Read our full disclosure.
We compared every tirzepatide programme we could get a straight price out of, then ranked them on what you are billed in month two rather than what the advert promises in month one.
That distinction decides this list. Half the programmes here advertise a medication price and charge a membership on top of it, so a $99 headline becomes a $198 statement. Coreage Rx finishes first because it does not do that — and because, once the fees are added, nothing else is close on cost.
The ranking
| # | Provider | Advertised | True monthly | Score |
|---|---|---|---|---|
| 1 | Coreage Rx Top pick Best overall on true monthly cost | $149 | $199 | 4.5 |
| 2 | Mochi Health Insurance concierge support | $199 | $278 incl. $79 fee | 3.6 |
| 3 | Hims & Hers Widest range of formats | $199 | $238 incl. $39 fee | 3.5 |
| 4 | Ro Branded medication with insurance help | $149 | $448 incl. $149 fee | 3.5 |
| 5 | Zealthy Low-cost entry with insurance routing | $216 | $216 | 3.5 |
| 6 | LifeMD Insurance coordination | $75 | $149 | 3.5 |
| 7 | Noom Med Behaviour change alongside medication | $149 | $149 | 3.5 |
| 8 | Eden Low advertised medication price | $199 | $298 incl. $99 fee | 3.1 |
| 9 | Henry Meds Sublingual and oral formats | $399 | $449 | 3 |
| 10 | TrimRx All-inclusive compounded pricing | $349 | $399 | 2.9 |
| 11 | Willow Straightforward single-price plans | $399 | $399 | 2.9 |
| 12 | MEDVi Tablet and injection choice | $399 | $399 | 2.8 |
Scores come from the weighted rubric on how we rate. Prices checked 2026-09-18.
1. Coreage Rx — Best overall on true monthly cost
$199 a month, all in. That sounds like a low bar. In this market it is not. Most programmes quote a medication price and then bill a membership on top of it, so a $199 advert becomes a $298 charge in month two. Coreage Rx runs from $149 a month on the annual plan, or $199 month-to-month, and there is no second line item waiting behind it.
The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year. Full detail in our Coreage Rx tirzepatide review.
2. Mochi Health — Insurance concierge support
$278 a month, all in. Compounded tirzepatide is around $199 a month with a $79 monthly membership on top, so roughly $278 all in — less if you prepay, since longer terms bring the membership nearer $66 a month. Prepaid terms are listed at $199 for three months, $399 for six and $799 for twelve.
Labs are billed separately. Ask what the clinic expects to order before you sign up. Full detail in our Mochi Health tirzepatide review.
3. Hims & Hers — Widest range of formats
$238 a month, all in. The compounded injection is priced from $199 a month, which reads competitively until you notice the membership. That is $39 for the first month and continues afterwards, so the working figure is nearer $238. Branded Zepbound through the same platform is $1,899 a month, a number that puts the compounded option in context.
The advertised entry prices and the membership are separate charges. Add $39/month to whatever medication figure you were quoted. Full detail in our Hims & Hers tirzepatide review.
4. Ro — Branded medication with insurance help
$448 a month, all in. Ro Body costs $39 for the first month and $149 a month after that, and the membership does not include any medication at all. Branded Zepbound is billed separately, typically $299 to $499 a month through manufacturer self-pay channels. Cash payers commonly end up somewhere between $298 and $598 a month.
The membership and the medication are two separate bills. A $39 first month does not mean a $39 prescription. Full detail in our Ro tirzepatide review.
5. Zealthy — Low-cost entry with insurance routing
$216 a month, all in. The first month is advertised at $39. After that the compounded pricing stands on its own, and because there is no recurring platform fee, the figure you are quoted is close to the figure you pay. That alone lifts it above several better-known competitors.
The widely quoted $25/month is an insured price. Cash payers should plan on $151+ for semaglutide. Full detail in our Zealthy tirzepatide review.
6. LifeMD — Insurance coordination
$149 a month, all in. The GLP-1 programme is $75 for the first month and $149 a month thereafter, with an annual plan bringing it as low as $75 a month. That fee buys clinical care and administrative work — not medication. If your insurer declines, you pay the fee and the full medication cost separately.
If your insurer declines, the $149/month programme fee still applies and the medication is extra. Full detail in our LifeMD tirzepatide review.
7. Noom Med — Behaviour change alongside medication
$149 a month, all in. Noom Med starts at $149 a month. There is also a lower-dose "microdose" programme from $79 a month with medication included, which is a genuinely different proposition and should not be compared on price against full-dose therapy.
A $79 microdose programme is not the same treatment as 10 mg tirzepatide. Check the dose before comparing on price. Full detail in our Noom Med tirzepatide review.
8. Eden — Low advertised medication price
$298 a month, all in. Membership starts at $39 as an introductory rate and renews at $99 a month, so the working cost from month two is close to $298. That is not hidden exactly — it is in the terms — but it is not what the landing page leads with, and it is the single largest factor in what you pay over a year.
The $99 semaglutide headline becomes roughly $198/month once the membership renews at its ongoing rate. Full detail in our Eden tirzepatide review.
What tirzepatide actually does
A single weekly injection that activates two gut hormone receptors, GIP and GLP-1, rather than one.
In SURMOUNT-1, adults with obesity lost an average of 19.5% of body weight on 10 mg and 20.9% on 15 mg over 72 weeks.
SURMOUNT-5 compared the two drugs directly. Participants on tirzepatide lost an average of 50.3 lb (22.8 kg); those on semaglutide lost 33.1 lb (15.0 kg).
Side effects reported most often: Nausea, diarrhoea, constipation and reflux, concentrated in the weeks after each dose increase. More on that in our plain-English guide to tirzepatide.
A word about compounded medication
Compounded GLP-1s are no longer the freely marketed product they were in 2024. They remain legal in a narrower form, and the rules changed again in 2026.
- A 503A pharmacy may still compound a GLP-1 for an individual patient when there is a documented, patient-specific clinical reason — for example a required dose or formulation that the approved product does not provide.
- Routinely marketed, off-the-shelf compounded GLP-1 sold like a consumer product is not permitted under that framework.
- If the 503B Bulks List proposal is finalised, outsourcing facilities would lose the pathway they have been using to produce these drugs in volume.
- Compounded versions are not FDA-approved. The agency does not review them for safety, effectiveness or manufacturing quality the way it reviews Zepbound or Wegovy.
We set the full timeline out in is compounded still legal, which we update whenever the FDA moves.
How we picked
- True monthly cost (30%) — What you actually pay in month two — medication plus membership plus anything billed separately. Advertised teaser rates score nothing here.
- Price honesty (20%) — Whether the renewal price is visible before you hand over a card, and whether the number at checkout matches the number in the ad.
- Clinical support (20%) — Who prescribes, how you reach them between visits, and whether dose changes are reviewed by a person or applied on a schedule.
- Pharmacy sourcing (15%) — Whether the provider names its pharmacy, states the 503A/503B pathway, and offers FDA-approved options alongside compounded ones.
- Cancelling (15%) — How hard it is to stop. Prepaid multi-month plans that cannot be refunded are marked down here.
We do not accept payment for placement in this table. We do earn a commission if you sign up with Coreage Rx through our link, which is disclosed at the top of this page and in full on our advertising disclosure.
Read next
- Coreage Rx tirzepatide review
Best overall on true monthly cost. We checked the advertised price against what you are actually billed. True cost: $199 a month.
- The best semaglutide providers in 2026
9 programmes compared on what you actually pay in month two — not the teaser rate. Coreage Rx comes first.
- The cheapest GLP-1 programmes, ranked honestly
Every provider ordered by what you pay in month two, with membership fees included and teaser rates thrown out.
- What you actually pay
Six pricing tricks that turn a $99 advert into a $298 statement, and how to check before you hand over a card.
- Tirzepatide vs semaglutide
One trial put them head to head. The result was not close — but the cheaper drug still wins for some people.