The best tirzepatide providers in 2026

We compared every tirzepatide programme we could get a straight price out of, then ranked them on what you are billed in month two rather than what the advert promises in month one.

That distinction decides this list. Half the programmes here advertise a medication price and charge a membership on top of it, so a $99 headline becomes a $198 statement. Coreage Rx finishes first because it does not do that — and because, once the fees are added, nothing else is close on cost.

The ranking

Scores come from the weighted rubric on how we rate. Prices checked 2026-09-18.

1. Coreage Rx — Best overall on true monthly cost

$199 a month, all in. The current tirzepatide schedule is $199 for one month, $159 a month for three, $139 for six and $129 for twelve. The starting rate belongs to a twelve-month plan totalling $1,548. Dose-flat pricing does not remove that commitment; check the refund and refill terms before paying.

The $79 semaglutide and $129 tirzepatide rates require 12-month plans. One-month plans are $139 and $199 respectively. Read the payment and refund terms before committing to a longer plan. Full detail in our Coreage Rx tirzepatide review.

2. SuperHealthy Rx — Public offer; not independently scored

$135 a month, all in. Online provider review for compounded semaglutide and tirzepatide; provider visit and shipping included according to the offer.

Confirm the total upfront payment, renewal, state availability and dispensing pharmacy. Full detail in our SuperHealthy Rx tirzepatide review.

3. Likeness Rx — Public offer; not independently scored

$199 a month, all in. These are provider-published terms checked October 4, 2026. Prescription approval is conditional. Compounded medications are not FDA-approved; we have not tested the treatment, pharmacy fulfillment or patient outcomes.

The lowest monthly equivalents accompany 12-month subscriptions: $948 for semaglutide or $1,548 for tirzepatide. One-month plans are $139 and $199. The page says the selected term renews automatically; check the amount due and cancellation date. Full detail in our Likeness Rx tirzepatide review.

4. Trimi — Lowest flat price with named pharmacies

$125 a month, all in. That second part matters more than the first. Most programmes on this site will not name their compounding pharmacy at all. Trimi names two — VialsRx, with a Texas Board of Pharmacy licence number, and GreenwichRx — and says a certificate of analysis is available if you ask. In a category where "who actually made this vial" is the hardest question to get answered, that is a genuine difference.

Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Full detail in our Trimi tirzepatide review.

5. PlexusDx — Pharmacy transparency and genetic testing

$189 a month, all in. Compounded injection pricing sits at $189 a month with no membership fee and the same price at every dose. The advertised "from $129" is the programme floor rather than the injection tier, so budget from $189. That is still well below most of this market.

The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Full detail in our PlexusDx tirzepatide review.

6. Ozari Health — Lowest advertised semaglutide price

$125 a month, all in. It also advertises semaglutide at $86 — the cheapest figure we have verified anywhere. Free expedited shipping is included, HSA and FSA cards are accepted, and there is no subscription to cancel.

Confirm whether $86 is a month-to-month rate or requires a longer commitment, and ask which pharmacy compounds it. Full detail in our Ozari Health tirzepatide review.

7. Fifty 410 — Prepaid blocks with no subscription

$133 a month, all in. That last part is unusual and genuinely useful. There is no membership, no recurring charge and nothing to cancel; you buy a block and it ends. Higher doses move you to the $549 block, or $183 a month.

The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments. Full detail in our Fifty 410 tirzepatide review.

8. Ivím Health — Unlimited clinician access

$199 a month, all in. Most programmes in this range hand you a portal and a shipping notification. Ivím reviews the dose weekly rather than on a fixed monthly calendar, which is a materially different model — closer to being someone’s patient than someone’s subscriber.

Pharmacy sourcing is not published. Ask which pharmacy fills your prescription and whether it is 503A or 503B before starting. Full detail in our Ivím Health tirzepatide review.

What tirzepatide actually does

A single weekly injection that activates two gut hormone receptors, GIP and GLP-1, rather than one.

In SURMOUNT-1, adults with obesity lost an average of 19.5% of body weight on 10 mg and 20.9% on 15 mg over 72 weeks.

SURMOUNT-5 compared the two drugs directly. Participants on tirzepatide lost an average of 50.3 lb (22.8 kg); those on semaglutide lost 33.1 lb (15.0 kg).

Side effects reported most often: Nausea, diarrhoea, constipation and reflux, concentrated in the weeks after each dose increase. More on that in our plain-English guide to tirzepatide.

A word about compounded medication

Compounded GLP-1s are no longer the freely marketed product they were in 2024. They remain legal in a narrower form, and the rules changed again in 2026.

• A 503A pharmacy may still compound a GLP-1 for an individual patient when there is a documented, patient-specific clinical reason — for example a required dose or formulation that the approved product does not provide.
• Routinely marketed, off-the-shelf compounded GLP-1 sold like a consumer product is not permitted under that framework.
• If the 503B Bulks List proposal is finalised, outsourcing facilities would lose the pathway they have been using to produce these drugs in volume.
• Compounded versions are not FDA-approved. The agency does not review them for safety, effectiveness or manufacturing quality the way it reviews Zepbound or Wegovy.
• The price argument for compounding is much weaker than it was. Two FDA-approved oral GLP-1s now start at $149 a month, and eligible Medicare beneficiaries can access certain GLP-1s for $50 a month from July 2026 — both below what many compounded programmes charge.

We set the full timeline out in is compounded still legal, which we update whenever the FDA moves.

How we picked

• True monthly cost (30%) — What you actually pay in month two — medication plus membership plus anything billed separately. Advertised teaser rates score nothing here.
• Price honesty (20%) — Whether the renewal price is visible before you hand over a card, and whether the number at checkout matches the number in the ad.
• Clinical support (20%) — Who prescribes, how you reach them between visits, and whether dose changes are reviewed by a person or applied on a schedule.
• Pharmacy sourcing (15%) — Whether the provider names its pharmacy, states the 503A/503B pathway, and offers FDA-approved options alongside compounded ones.
• Cancelling (15%) — How hard it is to stop. Prepaid multi-month plans that cannot be refunded are marked down here.

Coreage Rx is our paid featured partner and is pinned to first place in this table; every provider below it is in computed-score order. Scores are not adjusted for the arrangement — the unpinned score table, including any provider that outscores our featured pick, is published on how we rate and the commercial terms are on our advertising disclosure.