Guides

Plain-English guides

No jargon, no hedging. What the drugs do, what they cost, and what the rules are this year.

• Tirzepatide vs semaglutide

  One trial put them head to head. The result was not close — but the cheaper drug still wins for some people.

  Updated 2026-09-18

• Is compounded GLP-1 medication still legal?

  Short answer: yes, but in a much narrower form than in 2024 — and the FDA moved again this year.

  Updated 2026-09-18

• What you actually pay

  Six pricing tricks that turn a $99 advert into a $298 statement, and how to check before you hand over a card.

  Updated 2026-10-15

• Tirzepatide, explained plainly

  What it is, what it does to appetite, what the trials showed, and what the first three months tend to feel like.

  Updated 2026-09-18

• Semaglutide, explained plainly

  The drug behind Ozempic and Wegovy: how it works, what it costs, and how it compares to the newer option.

  Updated 2026-09-18

• How to spot a bad seller

  The FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.

  Updated 2026-09-18

• The twelve-month cost

  Month one is the cheapest month you will have. Here is the full-year arithmetic, including the costs nobody puts in the advert.

  Updated 2026-09-18

• Medicare, GLP-1s and the $50 month

  CMS is running a time-limited programme giving eligible Part D members certain GLP-1s for $50 a month. If you are on Medicare, read this before paying cash for anything.

  Updated 2026-09-18

• The approved pills changed the maths

  Two oral GLP-1s were approved either side of the new year, both starting at $149 a month. That undercuts a large part of the compounded market.

  Updated 2026-09-18

• What happens when you stop

  Most people regain a substantial share of the weight. Here is what the research actually found, and what that means for how you plan and budget.

  Updated 2026-09-18

• GLP-1s after 50

  These drugs work at any age. The risks are not identical at every age, and the muscle and bone question deserves more attention than it usually gets.

  Updated 2026-09-18

• Titration, properly explained

  When to step up, when to hold, when to go back down, and why restarting after a gap is the one genuinely dangerous mistake.

  Updated 2026-09-18

• How to read your prescription

  What the abbreviations mean, and the mg-versus-mL distinction that is the one genuine hazard in this category.

  Updated 2026-09-18