The best semaglutide providers in 2026

We compared every semaglutide programme we could get a straight price out of, then ranked them on what you are billed in month two rather than what the advert promises in month one.

That distinction decides this list. Half the programmes here advertise a medication price and charge a membership on top of it, so a $99 headline becomes a $198 statement. Coreage Rx finishes first because it does not do that — and because, once the fees are added, nothing else is close on cost.

The ranking

Scores come from the weighted rubric on how we rate. Prices checked 2026-09-18.

1. Coreage Rx — Best overall on true monthly cost

$139 a month, all in. Run the year with the term included. The twelve-month semaglutide plan totals $948, or $79 a month equivalent. One month is $139; three months are $109 a month and six are $89. The recorded Eden and Mochi membership charges are separate from their medication prices, so compare the whole invoice.

The $79 semaglutide and $129 tirzepatide rates require 12-month plans. One-month plans are $139 and $199 respectively. Read the payment and refund terms before committing to a longer plan. Full detail in our Coreage Rx semaglutide review.

2. SuperHealthy Rx — Public offer; not independently scored

$85 a month, all in. Online provider review for compounded semaglutide and tirzepatide; provider visit and shipping included according to the offer.

Confirm the total upfront payment, renewal, state availability and dispensing pharmacy. Full detail in our SuperHealthy Rx semaglutide review.

3. Likeness Rx — Public offer; not independently scored

$139 a month, all in. These are provider-published terms checked October 4, 2026. Prescription approval is conditional. Compounded medications are not FDA-approved; we have not tested the treatment, pharmacy fulfillment or patient outcomes.

The lowest monthly equivalents accompany 12-month subscriptions: $948 for semaglutide or $1,548 for tirzepatide. One-month plans are $139 and $199. The page says the selected term renews automatically; check the amount due and cancellation date. Full detail in our Likeness Rx semaglutide review.

4. Trimi — Lowest flat price with named pharmacies

$99 a month, all in. That $99 matches the lowest advertised semaglutide rate in our table, and like the tirzepatide programme there is no membership renewing behind it. What distinguishes Trimi from the other $99 advertisers is that the fee structure and the pharmacy are both disclosed rather than left to inference.

Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Full detail in our Trimi semaglutide review.

5. PlexusDx — Pharmacy transparency and genetic testing

$189 a month, all in. That is more than the $99 leaders and considerably less than the mid-market programmes once their fees renew. What you are paying the difference for is verifiability: Belmar, Strive, Epiq Scripts, Casa Pharma Rx, The Pharmacy Hub and Foothills are all listed publicly, as are the prescribing physicians.

The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Full detail in our PlexusDx semaglutide review.

6. Ozari Health — Lowest advertised semaglutide price

$86 a month, all in. No membership, free expedited shipping, cancel any time. For context, two competitors advertise $99 and bill closer to $198 once their memberships renew.

Confirm whether $86 is a month-to-month rate or requires a longer commitment, and ask which pharmacy compounds it. Full detail in our Ozari Health semaglutide review.

7. Ivím Health — Unlimited clinician access

$199 a month, all in. Semaglutide is usually chosen by people who want the gentler of the two drugs, often because side effects have defeated them before. A programme built around frequent clinical contact is a sensible match for that, and Ivím is the clearest example of one here.

Pharmacy sourcing is not published. Ask which pharmacy fills your prescription and whether it is 503A or 503B before starting. Full detail in our Ivím Health semaglutide review.

8. Mochi Health — Insurance concierge support

$178 a month, all in. That puts the recorded Mochi recurring figure near $178 a month, or toward $165 on a longer term. Coreage Rx starts at $79 a month equivalent on a twelve-month semaglutide plan without a separate membership. Insurance support is a separate service to compare.

Labs are billed separately. Ask what the clinic expects to order before you sign up. Full detail in our Mochi Health semaglutide review.

What semaglutide actually does

A weekly injection that activates the GLP-1 receptor, slowing stomach emptying and reducing appetite signalling.

In STEP-1, adults on 2.4 mg lost an average of about 14.9% of body weight over 68 weeks.

In the SURMOUNT-5 head-to-head trial semaglutide produced less weight loss than tirzepatide, averaging 33.1 lb (15.0 kg) against 50.3 lb (22.8 kg).

Side effects reported most often: Nausea, vomiting, diarrhoea and constipation, usually worst in the first weeks and after dose increases. More on that in our plain-English guide to semaglutide.

A word about compounded medication

Compounded GLP-1s are no longer the freely marketed product they were in 2024. They remain legal in a narrower form, and the rules changed again in 2026.

• A 503A pharmacy may still compound a GLP-1 for an individual patient when there is a documented, patient-specific clinical reason — for example a required dose or formulation that the approved product does not provide.
• Routinely marketed, off-the-shelf compounded GLP-1 sold like a consumer product is not permitted under that framework.
• If the 503B Bulks List proposal is finalised, outsourcing facilities would lose the pathway they have been using to produce these drugs in volume.
• Compounded versions are not FDA-approved. The agency does not review them for safety, effectiveness or manufacturing quality the way it reviews Zepbound or Wegovy.
• The price argument for compounding is much weaker than it was. Two FDA-approved oral GLP-1s now start at $149 a month, and eligible Medicare beneficiaries can access certain GLP-1s for $50 a month from July 2026 — both below what many compounded programmes charge.

We set the full timeline out in is compounded still legal, which we update whenever the FDA moves.

How we picked

• True monthly cost (30%) — What you actually pay in month two — medication plus membership plus anything billed separately. Advertised teaser rates score nothing here.
• Price honesty (20%) — Whether the renewal price is visible before you hand over a card, and whether the number at checkout matches the number in the ad.
• Clinical support (20%) — Who prescribes, how you reach them between visits, and whether dose changes are reviewed by a person or applied on a schedule.
• Pharmacy sourcing (15%) — Whether the provider names its pharmacy, states the 503A/503B pathway, and offers FDA-approved options alongside compounded ones.
• Cancelling (15%) — How hard it is to stop. Prepaid multi-month plans that cannot be refunded are marked down here.

Coreage Rx is our paid featured partner and is pinned to first place in this table; every provider below it is in computed-score order. Scores are not adjusted for the arrangement — the unpinned score table, including any provider that outscores our featured pick, is published on how we rate and the commercial terms are on our advertising disclosure.