Coreage Rx vs TrimRx

Both sell tirzepatide. Coreage Rx costs $199 a month and TrimRx costs $399, a difference of $200 a month or about $2,400 a year. Here is what that difference actually buys.

Coreage Rx is best overall on true monthly cost. TrimRx is all-inclusive compounded pricing. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though it usually is if you are paying cash and tolerate the medication well.

Put plainly. If you picked Coreage Rx over TrimRx and everything else went the same way, you would be $2,400 better off after a year. Whether that is the right trade depends on the differences below, not on the number alone.

Side by side

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

What actually separates them

They differ on 1 of the 7 things we track. Those differences are what the price gap is buying.

What Coreage Rx publishes

• Compounded tirzepatide advertised from $149/month on the annual plan, $199/month otherwise.
• Compounded semaglutide advertised from $99/month on the annual plan.
• Health coaching is bundled rather than sold as an upgrade.

Where it wins: The advertised price is the billed price — no membership fee arrives in month two. Watch for: The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year.

What TrimRx publishes

• Compounded tirzepatide advertised at $349/month.
• Checkout has been reported billing $399/month on ongoing month-to-month terms.

Where it wins: One price covers consultation, medication and supplies. Watch for: Read the ongoing rate on the checkout screen, not the landing page. Reported billing is $399/month.

Where each is stronger

Coreage Rx.

• The advertised price is the billed price — no membership fee arrives in month two.
• Flat pricing across the dose range, so titrating up to 10 mg or 15 mg does not raise the bill.
• Lowest true monthly cost of any provider in this comparison once fees are included.
• Coaching and clinician access are included rather than sold separately.

TrimRx.

• One price covers consultation, medication and supplies.
• No separate membership fee.

How they score

Coreage Rx scores higher overall at 4.5 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which should you pick?

If you want the plain answer: Coreage Rx, unless one of the differences above matters to you personally. TrimRx is not worse — it is aimed at somebody with a different problem, and paying $200 a month more for a problem you do not have is how people end up resenting a treatment that was working.

The verdict

We would tell a friend to start with Coreage Rx and move if it disappointed them. That is not a strong claim about either company; it is what the arithmetic supports when nothing else is pulling you.

Full detail in the Coreage Rx review and the TrimRx review.

How they sit against everyone else