Best of

Best value, not just cheapest

Where the money buys something — clinical support, sourcing transparency or flexibility — rather than simply being the lowest number.

Illustration of ascending stacked blocks

Updated 2026-09-18 · Prices verified independently


Cheapest and best value are different questions. This page is for the second one: where does each extra dollar actually buy something you can point at?

The test we applied is simple. If a programme costs more than the floor, we asked what the difference buys — unlimited clinician access, a named pharmacy, flat dose pricing, insurance advocacy — and whether that thing is worth the gap.

What qualifies for this list

  • Medication included in the monthly price.
  • Ranked on score per dollar — our overall rating divided by the billed monthly cost — rather than on score or price alone.
  • Fee-only and microdose programmes excluded, since their price is not comparable.

18 of the 21 providers we track qualify. Prices verified 2026-09-18 and re-checked periodically.

The list

#ProviderPer monthPer yearScore
1Coreage Rx$199$2,3884.5
2Trimi$125$1,5004.6
3Ozari Health$125$1,5004.4
4Fifty 410$133$1,5964.2
5PlexusDx$189$2,2684.4
6Ivím Health$199$2,3884
7Zealthy$216$2,5923.5
8Coby Health$239$2,8683.6
9Hims & Hers$238$2,8563.5
10Mochi Health$278$3,3363.6
11Eden$298$3,5763.1
12Lemonaid Health$348$4,1763.5
13Remedy Meds$399$4,7883.5
14Ro$448$5,3763.5
15TrimRx$399$4,7882.9
16Willow$399$4,7882.9
17MEDVi$399$4,7882.8
18Henry Meds$449$5,3883

Cheapest qualifying option: Trimi at $125 a month. Our featured partner is pinned to the top of the list where it qualifies — see how we rate for who scores higher.

1. Coreage Rx — Best overall on true monthly cost

$199 a month, no membership fee. Flat-rate telehealth program for compounded GLP-1s. The medication, the clinician visits and the ongoing check-ins are quoted as one number, with no separate membership billed alongside it.

The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year. Read the full Coreage Rx review.

2. Trimi — Lowest flat price with named pharmacies

$125 a month, no membership fee. Flat-rate compounded GLP-1 programme on annual plans, with medical oversight through the Arora Health clinician network and publicly named 503A compounding pharmacies.

Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Read the full Trimi review.

3. Ozari Health — Lowest advertised semaglutide price

$125 a month, no membership fee. Flat-rate compounded GLP-1 telehealth service operating in all 50 states, with physician review through the Arora Health network and a dedicated health concierge.

Confirm whether $86 is a month-to-month rate or requires a longer commitment, and ask which pharmacy compounds it. Read the full Ozari Health review.

4. Fifty 410 — Prepaid blocks with no subscription

$133 a month, no membership fee. Compounded GLP-1 telehealth platform selling prepaid three-month blocks with no membership, no subscription and no recurring charges.

The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments. Read the full Fifty 410 review.

5. PlexusDx — Pharmacy transparency and genetic testing

$189 a month, no membership fee. Prescription GLP-1 and peptide programmes with no membership fee, built around genetic testing, using independent clinicians and a publicly listed set of 503A pharmacies.

The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Read the full PlexusDx review.

Common questions

What is worth paying extra for?

In our view: a named compounding pharmacy, a price that holds across the dose ladder, and real clinical access when side effects hit. Those three change outcomes. Branding and app polish do not.

Is the most expensive programme the best?

No. The dearest programmes in our table are not the highest scoring, and several mid-priced ones outperform them on clinical support and disclosure.

What is the single biggest hidden cost?

A membership that renews higher than its introductory rate. It is the commonest reason a $99 advert becomes a $198 statement.

Read next

  • The best GLP-1 programmes

    Every provider we track, scored on the same five weighted criteria, whichever medication they dispense.

  • The most transparent providers

    Ranked on whether the advertised price is the billed price, and whether the company tells you where the medication comes from.

  • Flat pricing at every dose

    Programmes where the price does not rise as your dose does — which matters more over a year than most advertised discounts.

  • The cheapest tirzepatide online

    Every provider whose monthly price actually includes the medication, sorted on what you are billed in month two.

Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure