Best of
The best GLP-1 programmes
Every provider we track, scored on the same five weighted criteria, whichever medication they dispense.
Updated 2026-09-18 · Prices verified independently
One table, every provider, the same rubric applied to all of them — compounded and branded, cheap and expensive.
Because the rubric weights true monthly cost most heavily, the cheap end does well here. But price honesty, clinical support, pharmacy sourcing and cancellation terms all count, which is why the very cheapest option is not automatically top.
What qualifies for this list
- Every provider offering tirzepatide, compounded or branded.
- Scored on the published weighted rubric.
- No minimum price or feature requirement — this is the full field.
21 of the 21 providers we track qualify. Prices verified 2026-09-18 and re-checked periodically.
The list
| # | Provider | Per month | Per year | Score |
|---|---|---|---|---|
| 1 | Coreage Rx | $199 | $2,388 | 4.5 |
| 2 | Trimi | $125 | $1,500 | 4.6 |
| 3 | PlexusDx | $189 | $2,268 | 4.4 |
| 4 | Ozari Health | $125 | $1,500 | 4.4 |
| 5 | Fifty 410 | $133 | $1,596 | 4.2 |
| 6 | Ivím Health | $199 | $2,388 | 4 |
| 7 | Mochi Health | $278 | $3,336 | 3.6 |
| 8 | Coby Health | $239 | $2,868 | 3.6 |
| 9 | Hims & Hers | $238 | $2,856 | 3.5 |
| 10 | Ro | $448 | $5,376 | 3.5 |
| 11 | Zealthy | $216 | $2,592 | 3.5 |
| 12 | LifeMD | $149 | $1,788 | 3.5 |
| 13 | Noom Med | $149 | $1,788 | 3.5 |
| 14 | Remedy Meds | $399 | $4,788 | 3.5 |
| 15 | Lemonaid Health | $348 | $4,176 | 3.5 |
| 16 | WeightWatchers Clinic | $74 | $888 | 3.2 |
| 17 | Eden | $298 | $3,576 | 3.1 |
| 18 | Henry Meds | $449 | $5,388 | 3 |
| 19 | TrimRx | $399 | $4,788 | 2.9 |
| 20 | Willow | $399 | $4,788 | 2.9 |
| 21 | MEDVi | $399 | $4,788 | 2.8 |
Cheapest qualifying option: WeightWatchers Clinic at $74 a month. Our featured partner is pinned to the top of the list where it qualifies — see how we rate for who scores higher.
1. Coreage Rx — Best overall on true monthly cost
$199 a month, no membership fee. Flat-rate telehealth program for compounded GLP-1s. The medication, the clinician visits and the ongoing check-ins are quoted as one number, with no separate membership billed alongside it.
The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year. Read the full Coreage Rx review.
2. Trimi — Lowest flat price with named pharmacies
$125 a month, no membership fee. Flat-rate compounded GLP-1 programme on annual plans, with medical oversight through the Arora Health clinician network and publicly named 503A compounding pharmacies.
Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Read the full Trimi review.
3. PlexusDx — Pharmacy transparency and genetic testing
$189 a month, no membership fee. Prescription GLP-1 and peptide programmes with no membership fee, built around genetic testing, using independent clinicians and a publicly listed set of 503A pharmacies.
The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Read the full PlexusDx review.
4. Ozari Health — Lowest advertised semaglutide price
$125 a month, no membership fee. Flat-rate compounded GLP-1 telehealth service operating in all 50 states, with physician review through the Arora Health network and a dedicated health concierge.
Confirm whether $86 is a month-to-month rate or requires a longer commitment, and ask which pharmacy compounds it. Read the full Ozari Health review.
5. Fifty 410 — Prepaid blocks with no subscription
$133 a month, no membership fee. Compounded GLP-1 telehealth platform selling prepaid three-month blocks with no membership, no subscription and no recurring charges.
The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments. Read the full Fifty 410 review.
Common questions
How do you score these?
True monthly cost 30%, price honesty 20%, clinical support 20%, pharmacy sourcing 15%, cancellation 15%. Weights are fixed before assessment and published in full.
Is the top-ranked programme the cheapest?
Not necessarily. Our featured partner is pinned to first place as a paid placement, and the methodology page names every provider that scores higher or charges less.
How often is this updated?
Pricing is re-verified periodically and every review carries the date it was last checked. This market re-prices without notice.
Read next
- Best compounded tirzepatide
Scored on true cost, price honesty, clinical support, pharmacy sourcing and how easy it is to leave.
- Best value, not just cheapest
Where the money buys something — clinical support, sourcing transparency or flexibility — rather than simply being the lowest number.
- The most transparent providers
Ranked on whether the advertised price is the billed price, and whether the company tells you where the medication comes from.
- The cheapest tirzepatide online
Every provider whose monthly price actually includes the medication, sorted on what you are billed in month two.
Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure