Cheapest GLP-1 without insurance

If you have no coverage, or your insurer has already said no, the calculation is simple: which programme delivers medication for the smallest monthly number without an insurer involved at all.

We have deliberately excluded the programmes built around insurance coordination here. They can be excellent — but their value depends entirely on a claim being approved, and a fee for insurance advocacy is dead weight if you are paying cash regardless.

What qualifies for this list

• Cash-pay programmes where the medication is included in the monthly price.
• Programmes whose main value is insurance coordination are excluded — see the insurance page for those.
• No prior authorisation or coverage approval required to get the quoted price.

11 of the 21 providers we track qualify. Prices verified 2026-09-18 and re-checked periodically.

The list

Cheapest qualifying option: Ozari Health at $86 a month. Our featured partner is pinned to the top of the list where it qualifies — see how we rate for who scores higher.

1. Coreage Rx — Best overall on true monthly cost

$149 a month, no membership fee. Flat-rate telehealth program for compounded GLP-1s. The medication, the clinician visits and the ongoing check-ins are quoted as one number, with no separate membership billed alongside it.

The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year. Read the full Coreage Rx review.

2. Ozari Health — Lowest advertised semaglutide price

$86 a month, no membership fee. Flat-rate compounded GLP-1 telehealth service operating in all 50 states, with physician review through the Arora Health network and a dedicated health concierge.

Confirm whether $86 is a month-to-month rate or requires a longer commitment, and ask which pharmacy compounds it. Read the full Ozari Health review.

3. Trimi — Lowest flat price with named pharmacies

$99 a month, no membership fee. Flat-rate compounded GLP-1 programme on annual plans, with medical oversight through the Arora Health clinician network and publicly named 503A compounding pharmacies.

Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Read the full Trimi review.

4. Hims & Hers — Widest range of formats

$188 a month, including the $39 fee. Large publicly traded telehealth platform. Sells oral kits, compounded injections and branded Zepbound side by side, with a membership required across the board.

The advertised entry prices and the membership are separate charges. Add $39/month to whatever medication figure you were quoted. Read the full Hims & Hers review.

5. PlexusDx — Pharmacy transparency and genetic testing

$189 a month, no membership fee. Prescription GLP-1 and peptide programmes with no membership fee, built around genetic testing, using independent clinicians and a publicly listed set of 503A pharmacies.

The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Read the full PlexusDx review.

Common questions

Can I get a GLP-1 without insurance at all?

Yes. Every programme on this page is cash-pay and does not bill insurance. You will still need a prescription from a licensed clinician, which is included in the price.

Are HSA or FSA cards accepted?

Commonly yes — several providers accept them explicitly, which effectively pays with pre-tax dollars. Check with the specific provider before assuming.

Would Medicare be cheaper?

For eligible beneficiaries, almost certainly. From 1 July 2026 CMS is running a programme giving eligible Part D members certain GLP-1s for $50 a month, which undercuts every cash price here.