Best of
Zepbound alternatives
Zepbound is tirzepatide. Here is what else delivers the same molecule, what it costs, and what you give up.
Updated 2026-09-18 · Prices verified independently
Zepbound is Eli Lilly’s brand of tirzepatide, approved for weight management. Self-pay pricing has been listed around $299 to $499 a month, which is what sends most people looking for alternatives.
The realistic alternatives fall into two groups: compounded tirzepatide, which is the same molecule prepared by a pharmacy and not FDA-approved, and a different drug entirely such as semaglutide or one of the new approved pills. This page covers the first group, priced honestly.
What qualifies for this list
- Delivers tirzepatide — the same active ingredient as Zepbound.
- Monthly price includes the medication.
- Sorted cheapest first on the billed figure.
18 of the 21 providers we track qualify. Prices verified 2026-09-18 and re-checked periodically.
The list
Every row below is priced against Zepbound at $499 a month, and sorted by how much it saves you over a year. We use the $499 self-pay figure listed for the 5 mg, 7.5 mg and 10 mg single-dose vials; lower starting doses have been listed nearer $299. Ranked on our overall score rather than price alone — the cheapest option is on the cheapest tirzepatide page.
| # | Provider | Per month | Saves vs Zepbound | Per year |
|---|---|---|---|---|
| 1 | Coreage Rx | $199 | $3,600/yr | $2,388 |
| 2 | Trimi | $125 | $4,488/yr | $1,500 |
| 3 | PlexusDx | $189 | $3,720/yr | $2,268 |
| 4 | Ozari Health | $125 | $4,488/yr | $1,500 |
| 5 | Fifty 410 | $133 | $4,392/yr | $1,596 |
| 6 | Ivím Health | $199 | $3,600/yr | $2,388 |
| 7 | Mochi Health | $278 | $2,652/yr | $3,336 |
| 8 | Coby Health | $239 | $3,120/yr | $2,868 |
| 9 | Hims & Hers | $238 | $3,132/yr | $2,856 |
| 10 | Ro | $448 | $612/yr | $5,376 |
| 11 | Zealthy | $216 | $3,396/yr | $2,592 |
| 12 | Remedy Meds | $399 | $1,200/yr | $4,788 |
| 13 | Lemonaid Health | $348 | $1,812/yr | $4,176 |
| 14 | Eden | $298 | $2,412/yr | $3,576 |
| 15 | Henry Meds | $449 | $600/yr | $5,388 |
| 16 | TrimRx | $399 | $1,200/yr | $4,788 |
| 17 | Willow | $399 | $1,200/yr | $4,788 |
| 18 | MEDVi | $399 | $1,200/yr | $4,788 |
Cheapest qualifying option: Trimi at $125 a month. Our featured partner is pinned to the top of the list where it qualifies — see how we rate for who scores higher.
1. Coreage Rx — Best overall on true monthly cost
$199 a month, no membership fee. Flat-rate telehealth program for compounded GLP-1s. The medication, the clinician visits and the ongoing check-ins are quoted as one number, with no separate membership billed alongside it.
The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year. Read the full Coreage Rx review.
2. Trimi — Lowest flat price with named pharmacies
$125 a month, no membership fee. Flat-rate compounded GLP-1 programme on annual plans, with medical oversight through the Arora Health clinician network and publicly named 503A compounding pharmacies.
Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Read the full Trimi review.
3. PlexusDx — Pharmacy transparency and genetic testing
$189 a month, no membership fee. Prescription GLP-1 and peptide programmes with no membership fee, built around genetic testing, using independent clinicians and a publicly listed set of 503A pharmacies.
The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Read the full PlexusDx review.
4. Ozari Health — Lowest advertised semaglutide price
$125 a month, no membership fee. Flat-rate compounded GLP-1 telehealth service operating in all 50 states, with physician review through the Arora Health network and a dedicated health concierge.
Confirm whether $86 is a month-to-month rate or requires a longer commitment, and ask which pharmacy compounds it. Read the full Ozari Health review.
5. Fifty 410 — Prepaid blocks with no subscription
$133 a month, no membership fee. Compounded GLP-1 telehealth platform selling prepaid three-month blocks with no membership, no subscription and no recurring charges.
The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments. Read the full Fifty 410 review.
Common questions
Is compounded tirzepatide the same as Zepbound?
Same active ingredient, different product. Zepbound is manufactured and FDA-approved; compounded tirzepatide is prepared by a pharmacy against a prescription and has not been reviewed by the FDA for safety, effectiveness or manufacturing quality.
How much cheaper are the alternatives?
Verified compounded tirzepatide runs from about $125 a month against roughly $299 to $499 for self-pay Zepbound. Over a year that is a difference of several thousand dollars.
Is there a cheaper way to get Zepbound itself?
Possibly. Manufacturer self-pay channels have brought the price down considerably, and from July 2026 eligible Medicare beneficiaries may access certain GLP-1s for $50 a month.
Read next
- The cheapest tirzepatide online
Every provider whose monthly price actually includes the medication, sorted on what you are billed in month two.
- Best compounded tirzepatide
Scored on true cost, price honesty, clinical support, pharmacy sourcing and how easy it is to leave.
- FDA-approved, not compounded
Providers dispensing the manufacturers’ own products — Zepbound, Wegovy and the new approved pills — rather than compounded preparations.
- Wegovy alternatives
Wegovy is semaglutide. These are the cheaper routes to the same molecule, and the newer approved pill that changed the maths.
Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure